As I mentioned, I am currently up to my eyeballs in geek at the moment so blogging will be sparse for a few weeks, but there's always time to give Canadian IDiot Denyse O'Leary a good paddling:
Natural selection: Mutation protects against malaria - at a steep cost
Malaria, caused by a mosquito-borne parasite, Plasmodium falciparum, is one of humanity's most serious diseases, causing 500 million infections annually worldwide, and about one million deaths. . A recent study once again underlined the steep cost of "natural" protection...
... snip ...
However, the pyruvate kinase enzyme is needed to produce energy, so lacking it - or passing on a tendency to lack it - is not a very satisfactory solution. As Behe notes, it is "another example of a beneficial mutation turning out to be a degradative mutation."
See, I'll bet you never knew that biological evolution was somehow obligated to represent a perfect, monotonically-increasing progression to better and better life forms, did you? And the thought that some mutations might have both pros and cons? Inconceivable. Clearly an argument for a supreme designer.
Please, dear God, tell me it doesn't get any stupider than this. There's only so much I can take.